RSK2-IN-3
RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase[1].
Product Specifications
CAS Number
[1627136-54-2]
UNSPSC
12352005
Target
Ribosomal S6 Kinase (RSK)
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rsk2-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(C)(C)CO)/C(C#N)=C/C1=CC2=C(NN=C2C3=CC(OC)=C(OC)C(OC)=C3)C=C1
Molecular Formula
C24H26N4O5
Molecular Weight
450.49
References & Citations
[1]Hall A, et al. Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. ACS Med Chem Lett. 2022 Jun 25;13 (7) :1099-1108.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RSK2
Curated Selection
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