RSK2-IN-3
RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase[1].
Product Specifications
CAS Number
1627136-54-2
UNSPSC
12352005
Target
Ribosomal S6 Kinase (RSK)
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rsk2-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(C)(C)CO)/C(C#N)=C/C1=CC2=C(NN=C2C3=CC(OC)=C(OC)C(OC)=C3)C=C1
Molecular Formula
C24H26N4O5
Molecular Weight
450.49
References & Citations
[1]Hall A, et al. Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. ACS Med Chem Lett. 2022 Jun 25;13 (7) :1099-1108.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RSK2
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
IBCTGSSRC6HIS10UG 10 µg
Bacteria-Derived GSS Recombinant Protein C-6His Tag 10ug
Sign In for Pricing
View Details OR88748-01 100 mg
14- (4-Nitrophenoxy) -3,6,9,12-tetraoxatetradecan-1-ol
Sign In for Pricing
View Details