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HIV-1 inhibitor-44

HIV-1 inhibitor-44 (compound 11l) is a HIV-1 reverse transcriptase inhibitor. HIV-1 inhibitor-44 shows inhibitory activity against wild-type HIV-1 strain with an EC50 value of 0.209 μM[1].

Product Specifications

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/hiv-1-inhibitor-44.html

Solubility

10 mM in DMSO

Smiles

O=C1NC(C(C(C)C)=C(S(C2=CC(C)=CC(C)=C2)=O)N1COCC3=CC=CC=C3)=O

Molecular Formula

C23H26N2O4S

Molecular Weight

426.53

References & Citations

[1]Hao Q, et al. Structure-Based design of [ (2-Hydroxyethoxy) methyl]-6- (phenylthio) -thymine derivatives as nonnucleoside HIV-1 reverse transcriptase Inhibitors: From HEPTs to Sulfinyl-substituted HEPTs. Bioorg Chem. 2022 Sep. 126:105880.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HIV-1

Frequently Asked Questions

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