HIV-1 inhibitor-44
HIV-1 inhibitor-44 (compound 11l) is a HIV-1 reverse transcriptase inhibitor. HIV-1 inhibitor-44 shows inhibitory activity against wild-type HIV-1 strain with an EC50 value of 0.209 μM[1].
Product Specifications
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-44.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C(C(C)C)=C(S(C2=CC(C)=CC(C)=C2)=O)N1COCC3=CC=CC=C3)=O
Molecular Formula
C23H26N2O4S
Molecular Weight
426.53
References & Citations
[1]Hao Q, et al. Structure-Based design of [ (2-Hydroxyethoxy) methyl]-6- (phenylthio) -thymine derivatives as nonnucleoside HIV-1 reverse transcriptase Inhibitors: From HEPTs to Sulfinyl-substituted HEPTs. Bioorg Chem. 2022 Sep. 126:105880.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
Frequently Asked Questions
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