Antitumor agent-72

Antitumor agent-72 (compound 6w) is a potent anticancer agent. Antitumor agent-72 has anticancer activity and induces apoptosis through activation of caspase-3 and cleavage of PARP. Antitumor agent-72 can be used for cancer research[1].

Product Specifications

CAS Number

[2676942-92-8]

UNSPSC

12352005

Target

Apoptosis; Caspase; PARP

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-72.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(O)=C(C(OC)=C1OC)C(C2=CC3=CC=CN3C(C(C4=CC=C(Cl)C=C4)=O)=C2)=O

Molecular Formula

C25H20ClNO6

Molecular Weight

465.88

References & Citations

[1]Lee Y, et, al. Generation of a poly-functionalized indolizine scaffold and its anticancer activity in pancreatic cancer cells. Bioorg Chem. 2022 Sep;126:105877.