S07-2005 (racemic)
Product Specifications
UNSPSC Description
S07-2005 racemic is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. S07-2005 racemic has potential as a chemotherapeutic potentiator for cancer agent resistance[1].
Target Antigen
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s07-2005-racemic.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C)OC(CN(C)C(C2COC3=C(C=C(OCC)C=C3)C2)=O)=C1)O
Molecular Weight
373.40
References & Citations
[1]Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150649/S07-2005-racemic-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150649/
Clinical Information
No Development Reported
CAS Number
1826337-40-9
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