SARS-CoV-2 nsp13-IN-6
SARS-CoV-2 nsp13-IN-6 (compound C5) is a potent SARS-CoV-2 non-structural protein 13 (nsp13) inhibitor with IC50 values of 27 and 33 μM for ssDNA+ ATPase and ssDNA- ATPase. SARS-CoV-2 nsp13-IN-6 can be used for researching anti-COVID-19[1].
Product Specifications
CAS Number
[951588-85-5]
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-nsp13-in-6.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(C=C1)N=C(NC(CN3C=NC4=NC(CCCC5)=C5C=C4C3=O)=O)S2
Molecular Formula
C21H19N5O3S
Molecular Weight
421.47
References & Citations
[1]Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
141567 200 µL
Myosin Light Chain Kinase (MYLK, KRP, MLCK108, MLCK210, MSTP083, MLCK, smMLCK, MYLK1, MLCK1, Smooth Muscle Myosin Light Chain Kinase)
Ask
View Details MBS6254202-01 0.1 mL
Prostate Specific Antigen (PSA, APS, Gamma Seminoprotein, hK3, Kallikrein 3, Kallikrein-3, Kallikrein-related Peptidase 3, KLK3, KLK2A1, P-30 Antigen, Semenogelase, Seminin) (MaxLight 490)
Ask
View Details 
MBS6254202-02 5x 0.1 mL
Prostate Specific Antigen (PSA, APS, Gamma Seminoprotein, hK3, Kallikrein 3, Kallikrein-3, Kallikrein-related Peptidase 3, KLK3, KLK2A1, P-30 Antigen, Semenogelase, Seminin) (MaxLight 490)
Ask
View Details 
MBS1344471-01 0.02 mg (E-Coli)
Recombinant Neisseria meningitidis serogroup B Probable transcriptional regulatory protein NMB1648 (NMB1648)
Ask
View Details MBS1344471-02 0.1 mg (E-Coli)
Recombinant Neisseria meningitidis serogroup B Probable transcriptional regulatory protein NMB1648 (NMB1648)
Ask
View Details 
MBS1344471-03 0.02 mg (Yeast)
Recombinant Neisseria meningitidis serogroup B Probable transcriptional regulatory protein NMB1648 (NMB1648)
Ask
View Details