SARS-CoV-2 nsp13-IN-6

SARS-CoV-2 nsp13-IN-6 (compound C5) is a potent SARS-CoV-2 non-structural protein 13 (nsp13) inhibitor with IC50 values of 27 and 33 μM for ssDNA+ ATPase and ssDNA- ATPase. SARS-CoV-2 nsp13-IN-6 can be used for researching anti-COVID-19[1].

Product Specifications

CAS Number

[951588-85-5]

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-nsp13-in-6.html

Solubility

10 mM in DMSO

Smiles

COC1=CC2=C(C=C1)N=C(NC(CN3C=NC4=NC(CCCC5)=C5C=C4C3=O)=O)S2

Molecular Formula

C21H19N5O3S

Molecular Weight

421.47

References & Citations

[1]Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.