SARS-CoV-2 nsp13-IN-5
SARS-CoV-2 nsp13-IN-5 (compound C6) is a potent SARS-CoV-2 nsp13 inhibitor with IC50 values of 50 and 55 μM for ssDNA+ ATPase and ssDNA- ATPase. SARS-CoV-2 nsp13-IN-5 can be used for researching anti-COVID-19[1].
Product Specifications
CAS Number
912799-11-2
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-nsp13-in-5.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C=C1)CNC(CCCN(C(C2=C3C=CS2)=O)C(N3CC(NC4=C(C)C=CC=C4C)=O)=O)=O
Molecular Formula
C28H30N4O4S
Molecular Weight
518.63
References & Citations
[1]Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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