SARS-CoV-2 nsp13-IN-4
SARS-CoV-2 nsp13-IN-4 (C4 (d) ) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is agentlike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect[1].
Product Specifications
CAS Number
923140-39-0
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-nsp13-in-4.html
Solubility
10 mM in DMSO
Smiles
CC1=NC2=NC(C3=CC=C(C=C3)NC(C4=CC=CC(Br)=C4)=O)=CN2C=C1
Molecular Formula
C20H15BrN4O
Molecular Weight
407.26
References & Citations
[1]Aliakbar Khalili Yazdi, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040679-500 1x 500 µL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400282-100 1x 100 µL
HER-2 / CD340 (HRB2/282), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942302-500 1x 500 µL
MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) (rMUC18/1130), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC701841-500 1x 500 µL
Cytokeratin 7 (Glandular and Transitional Epithelial Marker) (rOV-TL12/30), CF770 conjugate, 0.1mg/mL
Sign In for Pricing
View Details