Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SphK1-IN-2

SphK1-IN-2 is a potent, selective SphK1 inhibitor with IC50 values of 19.81 nM and > 10 μM for SphK1 and SphK2, respectively. SphK1-IN-2 exhibits anti-proliferative activities and induces cell cycle arrest and apoptosis. SphK1-IN-2 can be used for cancer research[1].

Product Specifications

CAS Number

3031483-60-7

UNSPSC

12352005

Target

Apoptosis; SphK

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sphk1-in-2.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1N(CC2=CC=C(COC3=CC(CS(=O)(C4=CC=CC=C4)=O)=C(Br)C(C)=C3)C=C2)CCC1

Molecular Formula

C27H30BrNO4S

Molecular Weight

544.50

References & Citations

[1]Zhang S, et, al. Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer. J Med Chem. 2022 Jun 9;65 (11) :7697-7716.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

SphK1; SphK2

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Recombinant HCoV-229E S1+S2 Protein (ECD, His Tag)
PKSV030115 100 µg

Recombinant HCoV-229E S1+S2 Protein (ECD, His Tag)

Sign In for Pricing
View Details
BC034069 (BC034069) Mouse Tagged ORF Clone
MG201121 10 µg

BC034069 (BC034069) Mouse Tagged ORF Clone

Sign In for Pricing
View Details
CD47 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3B10]
TA813980BM 100 µL

CD47 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3B10]

Sign In for Pricing
View Details
ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF488A conjugate, 0.1mg/mL
BNC882035-100 1x 100 µL

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CBARA1 (MICU1) Human Gene Knockout Kit (CRISPR)
KN200921LP 1 Kit

CBARA1 (MICU1) Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Bromhexine Hydrochloride
TRC-B678600-50MG 50 mg

Bromhexine Hydrochloride

Sign In for Pricing
View Details