Estrogen receptor-IN-1

Estrogen receptor-IN-1 (compound 16) is a potent estrogen receptor (ER) inhibitor with IC50s of 13, 5µM for ERα and Erβ, respectively[1].

Product Specifications

CAS Number

[74027-99-9]

UNSPSC

12352005

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/estrogen-receptor-in-1.html

Purity

99.87

Solubility

DMSO : ≥ 100 mg/mL

Smiles

OC1=CC=C([Si](C)(C)C2=CC=CC=C2)C=C1

Molecular Formula

C14H16OSi

Molecular Weight

228.36

References & Citations

[1]Saito H, et al. Phosphine boranes as less hydrophobic building blocks than alkanes and silanes: Structure-property relationship and estrogen-receptor-modulating potency of 4-phosphinophenol derivatives. Bioorg Med Chem. 2020 Feb 15;28 (4) :115310.