NS2B/NS3-IN-7
Product Specifications
UNSPSC Description
NS2B/NS3-IN-7 (compound 26) is a highly potent Zika virus NS2B-NS3 protease inhibitor with a Ki value of 2.33 nM. NS2B/NS3-IN-7 can reduce amounts of ZIKV-infected cells[1].
Target Antigen
Flavivirus; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ns2b-ns3-in-7.html
Solubility
10 mM in DMSO
Smiles
NCCCC[C@@H](C(N[C@H]1CCCCN)=O)NC(CC2=CC=CC(CNC([C@@H](CCC3CCCCC3)NC([C@@H](CCCCNC1=O)NC(N)=N)=O)=O)=C2)=O
Molecular Weight
740.98
References & Citations
[1]Huber S, et al. Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors. J Med Chem. 2022 May 12;65(9):6555-6572.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150600/NS2B-NS3-IN-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150600/
Clinical Information
No Development Reported
CAS Number
3035421-16-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items