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NS2B/NS3-IN-7

Product Specifications

UNSPSC Description

NS2B/NS3-IN-7 (compound 26) is a highly potent Zika virus NS2B-NS3 protease inhibitor with a Ki value of 2.33 nM. NS2B/NS3-IN-7 can reduce amounts of ZIKV-infected cells[1].

Target Antigen

Flavivirus; Virus Protease

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ns2b-ns3-in-7.html

Solubility

10 mM in DMSO

Smiles

NCCCC[C@@H](C(N[C@H]1CCCCN)=O)NC(CC2=CC=CC(CNC([C@@H](CCC3CCCCC3)NC([C@@H](CCCCNC1=O)NC(N)=N)=O)=O)=C2)=O

Molecular Weight

740.98

References & Citations

[1]Huber S, et al. Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors. J Med Chem. 2022 May 12;65(9):6555-6572.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-150600/NS2B-NS3-IN-7-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-150600/

Clinical Information

No Development Reported

CAS Number

3035421-16-7

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