HIV-1 inhibitor-43
Product Specifications
UNSPSC Description
HIV-1 inhibitor-43 is a potent HIV-1 inhibitor with an EC50 of 21.3 nM, 6.2 nM, [1].
Target Antigen
DNA/RNA Synthesis; HIV
Type
Reference compound
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-43.html
Solubility
10 mM in DMSO
Smiles
O=C(C(N1)=C(S(=O)(C2=CC(C)=CC(C)=C2)=O)C3=C1C=CC(Cl)=C3)NCC4=CC=CC=C4O
Molecular Weight
468.95
References & Citations
[1]Nalli M, et al. New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains. Eur J Med Chem. 2020 Dec 15;208:112696.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150599/HIV-1-inhibitor-43-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150599/
Clinical Information
No Development Reported
CAS Number
2493426-43-8
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