Chitin synthase inhibitor 3
Chitin synthase inhibitor 3 (compound 2d) is a potent chitin synthase inhibitor with an IC50 value of 0.16 mM, and MIC of 1 µg/mL against candida albicans. Antifungal activity[1].
Product Specifications
CAS Number
[2416338-26-4]
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/chitin-synthase-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=CC=C1OC)/C=C/C(NC2C(NC3=C(C=CC=C3)C2)=O)=O
Molecular Formula
C20H19N3O4
Molecular Weight
365.38
References & Citations
[1]Li B, et al. Design, synthesis and biological evaluation of novel 3,4-dihydro-2 (1H) -quinolinone derivatives as potential chitin synthase inhibitors and antifungal agents. Eur J Med Chem. 2020 Jun 1;195:112278.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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