Chitin synthase inhibitor 3

Chitin synthase inhibitor 3 (compound 2d) is a potent chitin synthase inhibitor with an IC50 value of 0.16 mM, and MIC of 1 µg/mL against candida albicans. Antifungal activity[1].

Product Specifications

CAS Number

[2416338-26-4]

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/chitin-synthase-inhibitor-3.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=CC=C1OC)/C=C/C(NC2C(NC3=C(C=CC=C3)C2)=O)=O

Molecular Formula

C20H19N3O4

Molecular Weight

365.38

References & Citations

[1]Li B, et al. Design, synthesis and biological evaluation of novel 3,4-dihydro-2 (1H) -quinolinone derivatives as potential chitin synthase inhibitors and antifungal agents. Eur J Med Chem. 2020 Jun 1;195:112278.