Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

CDK9-IN-19

CDK9-IN-19 is a highly potent and selective CDK9 inhibitor with an IC50 value of 2.0 nM. CDK9-IN-19 has excellent cellular antiproliferative activity, moderate pharmacokinetic property and low hERG inhibition. CDK9-IN-19 significantly induces tumour growth inhibition in an MV4-11 xenograft mice model. CDK9-IN-19 can be used for researching acute myeloid leukaemia (AML) [1].

Product Specifications

CAS Number

2479306-60-8

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk9-in-19.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C(C)=O)=C(N2CCOCC2)C3=C(O1)C=C(NC4=NC=C(F)C(C5=CC=C(F)C=C5OC)=N4)C=C3

Molecular Formula

C26H22F2N4O5

Molecular Weight

508.47

References & Citations

[1]Xu J, et al. Discovery of coumarin derivatives as potent and selective cyclin-dependent kinase 9 (CDK9) inhibitors with high antitumour activity. Eur J Med Chem. 2020 Aug 15;200:112424.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK9

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

N-Boc-D-alaninol
TRC-B600583-250MG 250 mg

N-Boc-D-alaninol

Sign In for Pricing
View Details
CCDC17 (NM_001190182) Human Over-expression Lysate
LC434337 20 µg

CCDC17 (NM_001190182) Human Over-expression Lysate

Sign In for Pricing
View Details
trans-Nerolidol
TRC-N385710-1G 1 g

trans-Nerolidol

Sign In for Pricing
View Details
Recombinant Human EPO Receptor/EPOR Protein (Fc Tag)
PKSH031462 100 µg

Recombinant Human EPO Receptor/EPOR Protein (Fc Tag)

Sign In for Pricing
View Details
CD33 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2B2]
TA506350BM 100 µL

CD33 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2B2]

Sign In for Pricing
View Details
Neuroligin 3 (NLGN3) Mouse Monoclonal Antibody [Clone ID: OTI3D10]
TA815022 100 µL

Neuroligin 3 (NLGN3) Mouse Monoclonal Antibody [Clone ID: OTI3D10]

Sign In for Pricing
View Details