α-Glucosidase-IN-11

α-Glucosidase-IN-11 is a highly permeable competitive α-glucosidase inhibitor with the IC50 value of 0.56 μM. α-Glucosidase-IN-11 binds to Trp residues in α-glucosidase and regulates protein folding. α-Glucosidase-IN-11 can be used to regulate blood glucose levels[1].

Product Specifications

CAS Number

[2411744-76-6]

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-11.html

Solubility

10 mM in DMSO

Smiles

O=C(OCC)C1=CC=C(N2C(CO)=CC=C2/C=C3OC(C4=C\3C=C(C)NC4=O)=O)C=C1

Molecular Formula

C23H20N2O6

Molecular Weight

420.41

References & Citations

[1]Tania Luthra, et al. Discovery of novel pyrido-pyrrolidine hybrid compounds as alpha-glucosidase inhibitors and alternative agent for control of type 1 diabetes. Eur J Med Chem. 2020 Feb 15;188:112034.