CYP1B1-IN-2
CYP1B1-IN-2 (compound 9j) is a potent and selective CYP1B1 (cytochrome P450 1B1) inhibitor, with an IC50 of 0.52 nM[1].
Product Specifications
CAS Number
727730-24-7
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyp1b1-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=CC=CC(C(F)(F)F)=C2)OC3=C1C=CC4=CC=CC=C43
Molecular Formula
C20H11F3O2
Molecular Weight
340.30
References & Citations
[1]Dong J, et al. Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors. Eur J Med Chem. 2020 Feb 1;187:111938.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP1
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