IAA65
IAA65 is a potent T-type calcium channel inhibitor with a IC50 value of 18.9 μM. IAA65 can be used for epilepsy research[1].
Product Specifications
CAS Number
2987139-96-6
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/iaa65.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC(CC(C)C1)=O)C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2
Molecular Formula
C16H13F6NO2
Molecular Weight
365.27
References & Citations
[1]Amaye IJ, et, al. Evaluation of potential anticonvulsant fluorinated N-benzamide enaminones as T-type Ca2+ channel blockers. Bioorg Med Chem. 2022 Jul 1;65:116766.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
T-type calcium channel
Frequently Asked Questions
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