HDAC-IN-44
Product Specifications
UNSPSC Description
HDAC-IN-44 is a HDAC inhibitor with the IC50 value of 61.2 nM. HDAC-IN-44 shows high anticancer activity towards multiple cancer cell lines[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-44.html
Solubility
10 mM in DMSO
Smiles
O=C(NO)CCCCCN(C1)C([C@]2([H])CC3=C([C@H](C4=CC=C(Br)C=C4)N2C1=O)NC5=C3C=CC=C5)=O
Molecular Weight
539.42
References & Citations
[1]Ahmed K ElHady et al. Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors. Bioorg Chem. 2020 May;98:103742.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150500/HDAC-IN-44-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150500/
Clinical Information
No Development Reported
CAS Number
2414921-46-1
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