Diclofenac-d4 (sodium)
Diclofenac-d4 (sodium) is the deuterium labeled Diclofenac sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
Product Specifications
CAS Number
154523-54-3
UNSPSC
12352005
Target
Apoptosis; COX
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Immunology/Inflammation
Field of Research
Inflammation/Immunology
Purity
99.49
Solubility
10 mM in DMSO|H2O : 10mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O[Na])CC(C([2H])=C([2H])C([2H])=C1[2H])=C1NC2=C(C=CC=C2Cl)Cl
Molecular Formula
C14H6D4Cl2NNaO2
Molecular Weight
322.16
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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