Diclofenac-d4
Diclofenac-d4 is the deuterium labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
Product Specifications
CAS Number
153466-65-0
UNSPSC
12352005
Hazard Statement
H301, H361, H373, H412
Target
Apoptosis; COX; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Purity
99.79
Solubility
10 mM in DMSO|DMSO : ≥ 30mg/mL|Ethanol : ≥ 30mg/mL
Smiles
OC(CC(C([2H])=C([2H])C([2H])=C1[2H])=C1NC2=C(C=CC=C2Cl)Cl)=O
Molecular Formula
C14H7D4Cl2NO2
Molecular Weight
300.17
Precautions
H301, H361, H373, H412
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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