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(±) -Naproxen-13C, d3

(±) -Naproxen-13C, d3 is the deuterium and 13C labeled (±) -Naproxen[1]. (±) -Naproxen ((Rac) -Naproxen) is a racemate of Naproxen (HY-15030) . Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively.

Product Specifications

CAS Number

[1261392-52-2]

UNSPSC

12352005

Hazard Statement

H301

Target

COX

Type

Isotope-Labeled Compounds

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

OC(C(C1=CC2=C(C=C1)C=C(C=C2)O[13C]([2H])([2H])[2H])C)=O

Molecular Formula

C13 13CH11D3O3

Molecular Weight

234.27

Precautions

P264-P270-P330-P405-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Curated Selection

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