OX01914
Product Specifications
UNSPSC Description
OX01914 is a water-solube and permeable utrophin modulator (upregulates utrophin protein levels), with an EC50 of 20.5 μM. OX01914 can be used in study of duchenne muscular dystrophy (DMD)[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ox01914.html
Solubility
10 mM in DMSO
Smiles
O=C(NN)C1=NC(C2=CC=CC=C2)=CC(C3=CC=CC=C3)=N1
Molecular Weight
290.32
References & Citations
[1]Vuorinen A, et al. Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy. Eur J Med Chem. 2021 Aug 5;220:113431.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150078/OX01914-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150078/
Clinical Information
No Development Reported
CAS Number
49676-35-9
Curated Selection
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