Utrophin modulator 1
Utrophin modulator 1 is a potent utrophin modulator (upregulates utrophin protein levels), with an EC50 of 0.11 μM. Utrophin modulator 1 can be used in study of duchenne muscular dystrophy (DMD) [1].
Product Specifications
CAS Number
3068935-32-7
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/utrophin-modulator-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NN)C1=NC(N2CC(C=CC=C3)=C3C2)=CC(C4=CC(N=CC=C5)=C5C=C4)=N1
Molecular Formula
C22H18N6O
Molecular Weight
382.42
References & Citations
[1]Chatzopoulou M, et al. Structure-activity relationships of 2-pyrimidinecarbohydrazides as utrophin modulators for the potential treatment of Duchenne muscular dystrophy. Bioorg Med Chem. 2022 Sep 1;69:116812.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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