STING agonist-18
STING agonist-18 (compound 1a) is a STING agonist that can be used for synthesis of antibody-drug conjugates (ADCs), such Trastuzumab conjugate[1].
Product Specifications
CAS Number
2138299-68-8
UNSPSC
12352005
Target
ADC Payload; STING
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sting-agonist-18.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C5=C(OCCCN)C=C(C(N)=O)C=C5N=C4NC(C6=CC(C)=NN6CC)=O
Molecular Formula
C38H45N13O6
Molecular Weight
779.85
References & Citations
[1]Jeremy R. Duvall, et al. Antibody drug conjugates comprising sting agonists. WO2021202984A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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