Antimalarial agent 15
Antimalarial agent 15 (Compound 4e) is a parasite inhibitor. Antimalarial agent 15 shows antimalarial activity, and can inhibit P. falciparum 3D7 parasite growth (IC50=20 nM) [1].
Product Specifications
CAS Number
956928-33-9
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-15.html
Solubility
10 mM in DMSO
Smiles
CCCCC1=CC(OC2=C1C(OCC(N3CC4=C(C5=C(N4)C=CC=C5)C[C@H]3C(OC)=O)=O)=CC(C)=C2)=O
Molecular Formula
C29H30N2O6
Molecular Weight
502.56
References & Citations
[1]Nobuo Cho, et al. New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2- ((coumarin-5-yl) oxy) alkanoyl moiety. Bioorg Med Chem. 2022 Jul 15;66:116830.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
Frequently Asked Questions
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