NVP-BBD130
NVP-BBD130 is a potent, stable, ATP-competitive and orally active dual PI3K and mTOR inhibitor[1]. NVP-BBD130 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
853910-61-9
UNSPSC
12352005
Target
MTOR; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nvp-bbd130.html
Solubility
10 mM in DMSO
Smiles
N#CC(C)(C)C1=CC=C(N2C(N(C)C3=CN=C4C=CC(C#CC5=CC=CN=C5)=CC4=C32)=O)C=C1
Molecular Formula
C28H21N5O
Molecular Weight
443.50
References & Citations
[1]Marone R, et al. Targeting melanoma with dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors. Mol Cancer Res. 2009 Apr;7 (4) :601-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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