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PI3K-IN-38

PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α) . PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1].

Product Specifications

CAS Number

1382979-64-7

UNSPSC

12352005

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pi3k-in-38.html

Solubility

10 mM in DMSO

Smiles

CC1(C)OCCN2C1=NC3=C(N4CCOCC4)N=C(C5=CC=C(N)C=C5)N=C23

Molecular Formula

C20H24N6O2

Molecular Weight

380.44

References & Citations

[1]Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI3Kα

Available Sizes

Frequently Asked Questions

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