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CB1/2 agonist 2

CB1/2 agonist 2 (compound 23) is a potent non-selective cannabinoid ligand, with Ki values of 3.5 and 1.2 nM, respectively. CB1/2 agonist 2 can behave as a full CB1 agonist and CB2 competitive inverse agonist. CB1/2 agonist 2 shows antinociceptive activity[1].

Product Specifications

CAS Number

2772379-97-0

UNSPSC

12352005

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cb1-2-agonist-2.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1CC1)CCCCCCCCCCOC2=CC(CCCCC)=CC(OC)=C2

Molecular Formula

C26H43NO3

Molecular Weight

417.62

References & Citations

[1]Brizzi A, et al. Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity. Bioorg Med Chem. 2020 Jun 1;28 (11) :115513.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CB1; CB2

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