Anticancer agent 120

Anticancer agent 120 (compound 21) is an N-acylated ciprofloxacin derivative, which has certain antibacterial activity and induces ROS to promote cancer cell apoptosis[1].

Product Specifications

CAS Number

[2928614-22-4]

UNSPSC

12352005

Target

Apoptosis; Bacterial; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-120.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C(O)=O)=CN(C2CC2)C3=CC(N4CCN(CCCCCCCCCCC(N5CCN(C6=C(F)C=C7C(N(C8CC8)C=C(C(O)=O)C7=O)=C6)CC5)=O)CC4)=C(F)C=C13

Molecular Formula

C45H54F2N6O7

Molecular Weight

828.94

References & Citations

[1]Marta Struga, et al. N-Acylated Ciprofloxacin Derivatives: Synthesis and In Vitro Biological Evaluation as Antibacterial and Anticancer Agents. ACS Omega. 2023 May 18;8 (21) :18663-18684.