Pim-1 kinase inhibitor 6
Product Specifications
UNSPSC Description
Pim-1 kinase inhibitor 6 (Compound 4d) is a potent Pim-1 kinase inhibitor with IC50 value of 0.46 μM, and has significant cytotoxic effect on cancer cells[1].
Target Antigen
Pim
Type
Reference compound
Related Pathways
JAK/STAT Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pim-1-kinase-inhibitor-6.html
Solubility
10 mM in DMSO
Smiles
ClC(C(C1=CC(C2=CC=C(Br)C=C2)=NC(Cl)=C1C#N)=C3)=NC4=C3C=CC=C4
Molecular Weight
455.13
References & Citations
[1]Basem Mansour, et al. Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim-1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation. ACS Omega. 2023 May 24;8(22):19351-19366.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149996/Pim-1-kinase-inhibitor-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149996/
Clinical Information
No Development Reported
CAS Number
2928606-69-1
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