DS43260857
DS43260857 is a potentNaV1.7inhibitor, which has a high inhibitory effect on both human and mouse NaV1.7. The IC50 values of DS43260857 for hNaV1.1, hNaV1.5, hNaV1.7, mNaV1.7 are 6.6, 14, 0.015 and 0.061 μM, respectively[1].
Product Specifications
CAS Number
1612158-07-2
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ds43260857.html
Solubility
10 mM in DMSO
Smiles
CC1=CN(C2=CC(C(F)(F)F)=CN=C2)C3=C1C=C(C(NS(C4CC4)(=O)=O)=O)C=C3
Molecular Formula
C19H16F3N3O3S
Molecular Weight
423.41
References & Citations
[1]Narayan Karanjule, et al. N-Aryl Indoles as a Novel Class of Potent NaV1.7 Inhibitors. ACS Med Chem Lett. 2023 May 24;14 (6) :788-793.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC941747-100 1x 100 µL
CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) (Ki-1/1747R), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
![OSGIN2 Mouse Monoclonal Antibody [Clone ID: OTI1C7]](https://cdn.genprice.uk/products/937/68dd18ba061270361e908483/imageurl/cf808967.webp)
CF808967 100 µg
OSGIN2 Mouse Monoclonal Antibody [Clone ID: OTI1C7]
Sign In for Pricing
View Details 
