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HIV-1 inhibitor-56

Product Specifications

UNSPSC Description

HIV-1 inhibitor-56 (compound 12126065) is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor. HIV-1 inhibitor-56 has antiviral activity against wild-type HIV-1 in TZM cells with an EC50 value of 0.24 nM. HIV-1 inhibitor-56 penetrates the blood-brain barrier[1].

Target Antigen

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hiv-1-inhibitor-56.html

Solubility

10 mM in DMSO

Smiles

N#C/C=C/C1=CC2=C(C(S(N3C(N)=NC(NC4=CC=C(C#N)C(Cl)=C4)=N3)(=O)=O)=CC=C2)C=C1

Molecular Weight

475.91

References & Citations

[1]Lane T, et, al. N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine as a New Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor. J Med Chem. 2023 May 11;66(9):6193-6217.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-149991/HIV-1-inhibitor-56-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-149991/

Clinical Information

No Development Reported

CAS Number

2952530-45-7

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