HIV-1 inhibitor-56
HIV-1 inhibitor-56 (compound 12126065) is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor. HIV-1 inhibitor-56 has antiviral activity against wild-type HIV-1 in TZM cells with an EC50 value of 0.24 nM. HIV-1 inhibitor-56 penetrates the blood-brain barrier[1].
Product Specifications
CAS Number
[2952530-45-7]
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-56.html
Solubility
10 mM in DMSO
Smiles
N#C/C=C/C1=CC2=C(C(S(N3C(N)=NC(NC4=CC=C(C#N)C(Cl)=C4)=N3)(=O)=O)=CC=C2)C=C1
Molecular Formula
C22H14ClN7O2S
Molecular Weight
475.91
References & Citations
[1]Lane T, et, al. N-Phenyl-1- (phenylsulfonyl) -1H-1,2,4-triazol-3-amine as a New Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor. J Med Chem. 2023 May 11;66 (9) :6193-6217.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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