P-gp inhibitor 13

P-gp inhibitor 13 is a P-gp inhibitor. P-gp inhibitor 13 can reverse P-glycoprotein-mediated paclitaxel resistance in A2780/T cell. P-gp inhibitor 13 can be used for the research of advanced acute myeloid leukemia[1].

Product Specifications

CAS Number

[3041121-57-4]

UNSPSC

12352005

Target

P-glycoprotein

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/p-gp-inhibitor-13.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(CC(OCC2=C3OC(C(CC4=CC=CC=C4)=C(C3=CC=C2OC(C)C)C)=O)=O)=CC(OC)=C1OC

Molecular Formula

C32H34O8

Molecular Weight

546.61

References & Citations

[1]Wang W, et al. Design, synthesis and biological evaluation of seco-DSP/DCK derivatives reversing P-glycoprotein-mediated paclitaxel resistance in A2780/T cells. Eur J Med Chem. 2023;250:115218.