Antitumor agent-96

Antitumor agent-96 (Compound D34) is a potent MRE11 inhibitor. Antitumor agent-96 down-regulates the HR pathway by binding with MRE11 and suppressing its endonuclease functions. Antitumor agent-96 induces CM cells apoptosis[1].

Product Specifications

CAS Number

[3041063-90-2]

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-96.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C2C=CC=CC2=CC=C1OCCCN3CCNCC3)CCCC4=CC=CC=C4

Molecular Formula

C27H32N2O2

Molecular Weight

416.56

References & Citations

[1]Wei J, et al. Drug repurposing of propafenone to discover novel anti-tumor agents by impairing homologous recombination to delay DNA damage recovery of rare disease conjunctival melanoma. Eur J Med Chem. 2023 Mar 15;250:115238.