Antitumor agent-96
Antitumor agent-96 (Compound D34) is a potent MRE11 inhibitor. Antitumor agent-96 down-regulates the HR pathway by binding with MRE11 and suppressing its endonuclease functions. Antitumor agent-96 induces CM cells apoptosis[1].
Product Specifications
CAS Number
[3041063-90-2]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-96.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2C=CC=CC2=CC=C1OCCCN3CCNCC3)CCCC4=CC=CC=C4
Molecular Formula
C27H32N2O2
Molecular Weight
416.56
References & Citations
[1]Wei J, et al. Drug repurposing of propafenone to discover novel anti-tumor agents by impairing homologous recombination to delay DNA damage recovery of rare disease conjunctival melanoma. Eur J Med Chem. 2023 Mar 15;250:115238.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149972/Antitumor-agent-96-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149972/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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