XJ02862-S2

XJ02862-S2 shows potent FXR agonistic activity. XJ02862-S2 is a promising lead compound for the research of NAFLD[1].

Product Specifications

CAS Number

[3023355-55-4]

UNSPSC

12352005

Target

FXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/xj02862-s2.html

Solubility

10 mM in DMSO

Smiles

C[C@H]1C[C@H](C2=CC=CC=C2N1C([C@@H](N3C(C4CCCCC4C3=O)=O)C)=O)NC5=CC=CC=C5

Molecular Formula

C27H31N3O3

Molecular Weight

445.55

References & Citations

[1]Tong Qin, et al. Machine learning- and structure-based discovery of a novel chemotype as FXR agonists for potential treatment of nonalcoholic fatty liver disease. Eur J Med Chem. 2023 Apr 5;252:115307.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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