PROTAC CDK9 degrader-6
PROTAC CDK9 degrader-6 is a PROTAC targeting to CDK9 sepcifically. PROTAC CDK9 degrader-6 mediates CDK9 degradation via the proteasome. PROTAC CDK9 degrader-6 degrades CDK9 with DC50s of 0.10 μM and 0.14 μM for the CDK942 and CDK955 isoforms, respectively[1].
Product Specifications
CAS Number
[2935587-91-8]
UNSPSC
12352005
Target
CDK; PROTACs
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-cdk9-degrader-6.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCCCCCCCCC(N1CCC(CC1)NC(C2=NNC=C2NC(C3=C(C=CC=C3Cl)Cl)=O)=O)=O)CNC4=CC=CC(C(N5C6CCC(NC6=O)=O)=O)=C4C5=O
Molecular Formula
C42H49Cl2N9O8
Molecular Weight
878.80
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149963/PROTAC-CDK9-degrader-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149963/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK9
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