Antiparasitic agent-17

Antiparasitic agent-17 (compound 5u) is an orally active antiparasitic agent. Antiparasitic agent-17 inhibits Chloroquine sensitive (Pf3D7) and Chloroquine resistant (PfK1) strain with IC50s of 0.96 μM and 1.67 μM, respectively[1].

Product Specifications

CAS Number

[3043821-43-5]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antiparasitic-agent-17.html

Solubility

10 mM in DMSO

Smiles

CC(C)C1=CC=C(C2=C(C3=CC=CC=C3)C(C(NC4=CC=CC=C4)=O)=C(C)N2CC(C(O)O5)=CC5=O)C=C1

Molecular Formula

C32H30N2O4

Molecular Weight

506.59

References & Citations

[1]Alka Raj Pandey, et al. Design, synthesis and evaluation of novel pyrrole-hydroxybutenolide hybrids as promising antiplasmodial and anti-inflammatory agents. Eur J Med Chem. 2023 Jun 5;254:115340.