Mps1-IN-6
Mps1-IN-6 is a potent Mps1 inhibitor with an IC50 value of 2.596 nM. Mps1-IN-6 shows antiproliferative activity. Mps1-IN-6 shows antitumor activity[1].
Product Specifications
CAS Number
[3043761-59-4]
UNSPSC
12352005
Target
Mps1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mps1-in-6.html
Solubility
10 mM in DMSO
Smiles
CCC1=CC=CC(CC)=C1N2CCN3C=C(C=C3C2=O)C4=C5C=NNC5=NC(NC6=C(C=C(C=C6)N7CCN(CC7)C(C)=O)OC)=N4
Molecular Formula
C35H39N9O3
Molecular Weight
633.74
References & Citations
[1]Shihe Hu, et al. Discovery of pyrazolo[3,4-b]pyridine derivatives as novel and potent Mps1 inhibitors for the treatment of cancer. European Journal of Medicinal Chemistry. 2023, 253: 115334.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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