Antileishmanial agent-16
Antileishmanial agent-16 (compound 14c) is an anti-Leishmania agent. Antileishmanial agent-16 has superior anti-Leishmania major promastigotes activity (IC50 = 0.59 µM) and anti-Leishmania major amastigotes activity (IC50 = 0.81 µM) . Antileishmanial agent-16 has good safety to mammalian cells (VERO cells) [1].
Product Specifications
CAS Number
[2934738-41-5]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antileishmanial-agent-16.html
Solubility
10 mM in DMSO
Smiles
CCCCOC1=CC2=C(C=C(C(O2)=O)C(NCCCCCCN3C=C(N=N3)CN4CCCC4)=O)C=C1
Molecular Formula
C27H37N5O4
Molecular Weight
495.61
References & Citations
[1]Hassan NW, et al. Modulating leishmanial pteridine metabolism machinery via some new coumarin-1,2,3-triazoles: Design, synthesis and computational studies. Eur J Med Chem. 2023 May 5;253:115333.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2153759-01 0.01 mg
Recombinant Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)
Ask
View Details 
MBS2153759-02 0.05 mg
Recombinant Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)
Ask
View Details MBS2153759-03 0.1 mg
Recombinant Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)
Ask
View Details 
MBS2153759-04 0.2 mg
Recombinant Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)
Ask
View Details 
MBS2153759-05 0.5 mg
Recombinant Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)
Ask
View Details MBS2153759-06 1 mg
Recombinant Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)
Ask
View Details