Anticancer agent 105
Anticancer agent 105 is a compound based on thienopyrimidine scaffold, with with good safety and anticancer properties. Anticancer agent 105 shows selective toxicity towards melanoma cancer, and induces apoptosis. And Anticancer agent 105 significantly inhibits the metastatic nodules, even in pulmonary metastatic melanoma mouse model[1].
Product Specifications
CAS Number
2450987-57-0
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-105.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC)C1=C(NC(/C(O[K])=C(C(N)=O)\C#N)=C\C(C2=CC=C(OC)C=C2)=O)SC3=C1CCCC3
Molecular Formula
C25H24KN3O6S
Molecular Weight
533.64
References & Citations
[1]Rogova A, et al. Synthesis of thieno[3,2-e]pyrrolo[1,2-a]pyrimidine derivatives and their precursors containing 2-aminothiophenes fragments as anticancer agents for therapy of pulmonary metastatic melanoma. Eur J Med Chem. 2023 Jun 5;254:115325.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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