Analgesic agent-2
Product Specifications
UNSPSC Description
Analgesic agent-2 is a selective and orally active NaV1.8 Channel inhibitor, with an IC50 of 50.18 nM in HEK293 cells stably expressing human NaV1.8 channel. Analgesic agent-2 has analgesic activity[1].
Target Antigen
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/analgesic-agent-2.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C=C(C(N2CCCC(F)(CC2)F)=N1)C(NC3=CC4=C(CNC4=O)C=C3)=O)Cl
Molecular Weight
434.87
References & Citations
[1]Qin H, et al. Discovery of selective NaV1.8 inhibitors based on 5-chloro-2-(4,4-difluoroazepan-1-yl)-6-methyl nicotinamide scaffold for the treatment of pain. Eur J Med Chem. 2023 Jun 5;254:115371.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149944/Analgesic-agent-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149944/
Clinical Information
No Development Reported
CAS Number
2983892-65-3
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