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PAP-IN-2

PAP-IN-2 (Compound 35) is a purple acid phosphatase (PAP) inhibitor (Kis: 186 nM) . PAP-IN-2 can be used for development of anti-osteoporotic compounds[1].

Product Specifications

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pap-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(CCCCCCCCCCCCCCCCC)NC(P(O)(O)=O)C1=CC=C(OC)C=C1

Molecular Formula

C26H46NO5P

Molecular Weight

483.62

References & Citations

[1]Feder D, et al. Optimization of an α-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches. Eur J Med Chem. 2023 Jun 5;254:115383.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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