Antimalarial agent 25
Antimalarial agent 25 is an orally active 1,4-naphthoquinones derivative with antimalarial activity. Antimalarial agent 25 shows cytotoxicity against P. falciparum. Antimalarial agent 25 inhibits P. burghei induced parasitemia in vivo[1].
Product Specifications
CAS Number
2944456-41-9
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-25.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)C2=CN(N=N2)CCNC3=CC(C4=CC=CC=C4C3=O)=O
Molecular Formula
C21H18N4O3
Molecular Weight
374.39
References & Citations
[1]Costa Souza RM, et al. Biological activity of 1,2,3-triazole-2-amino-1,4-naphthoquinone derivatives and their evaluation as therapeutic strategy for malaria control. Eur J Med Chem. 2023 Jul 5;255:115400.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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