Antimalarial agent 24
Antimalarial agent 24 (Compound 7) is an antimalarial agent in vitro. Antimalarial agent 24 inhibits P. falciparum W2 strain with an IC50 of 0.81 μM. Antimalarial agent 24 displays a CC50 higher than 200 μM against HepG2 cells[1].
Product Specifications
CAS Number
2299199-54-3
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-24.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C(C2=C1C=CC=C2)=O)NCCN3N=NC(C4=CC=CC=C4)=C3
Molecular Formula
C20H16N4O2
Molecular Weight
344.37
References & Citations
[1]Costa Souza RM, et al, De Oliveira RN. Biological activity of 1,2,3-triazole-2-amino-1,4-naphthoquinone derivatives and their evaluation as therapeutic strategy for malaria control. Eur J Med Chem. 2023 Jul 5;255:115400.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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