EBL-3183
Product Specifications
UNSPSC Description
EBL-3183, an indole-2-carboxylate, is a potent metallo-β-lactamase (MBL) inhibitor. EBL-3183 is reversibly binding, non-covalent, competitive NDM-1 inhibitor with a pIC50 of 7.7[1].
Target Antigen
Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ebl-3183.html
Solubility
10 mM in DMSO
Smiles
C[C@H](N1C[C@]2(OC1=O)C[C@@H](C2)CN)C3=CC=CC4=C3NC(C(O)=O)=C4C5=CC=C(C(F)=C5)NS(C)(=O)=O
Molecular Weight
530.57
References & Citations
[1]Jürgen Brem, et al. Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors. Nat Chem. 2022 Jan;14(1):15-24.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149929/EBL-3183-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149929/
Clinical Information
No Development Reported
CAS Number
2872672-18-7
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