Antimalarial agent 23
Product Specifications
UNSPSC Description
Antimalarial agent 23 is an antimalarial benzimidazole with IC50s of 0.08 μM and 0.10 μM for PfNF54 and PfK1, respectively. Antimalarial agent 23 has potent β-hematin inhibition activity. Antimalarial agent 23 does not directly inhibit the conversion of heme to hemozoin[1].
Target Antigen
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-23.html
Solubility
10 mM in DMSO
Smiles
CCN(CC1=C(C=C(C=C1)Cl)O)CCNC2=NC=C3N=C(NC3=C2)C4=CC=CC(C(F)(F)F)=C4
Molecular Weight
489.92
References & Citations
[1]Henrietta D Attram, et al. Antimalarial Imidazopyridines Incorporating an Intramolecular Hydrogen Bonding Motif: Medicinal Chemistry and Mechanistic Studies. ACS Infect Dis. 2023 Apr 14;9(4):928-942.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149919/Antimalarial-agent-23-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149919/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![P Glycoprotein (ABCB1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6H2]](https://cdn.genprice.uk/genprice/genprice4.png)
TA801007AM 100 µL
P Glycoprotein (ABCB1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6H2]
Ask
View Details 