GY1-22
GY1-22 is an inhibitor of DNAJA1-mutP53R175H interacting pocket. GY1-22 can be used for the research of cancer[1].
Product Specifications
CAS Number
326903-84-8
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gy1-22.html
Solubility
10 mM in DMSO
Smiles
C1(N=C(SCC2=NC3=C(N2)C=CC=C3)N4CCOC5=CC=CC=C5)=C4C=CC=C1
Molecular Formula
C23H20N4OS
Molecular Weight
400.50
References & Citations
[1]Tong X, et al. Identification of a druggable protein-protein interaction site between mutant p53 and its stabilizing chaperone DNAJA1. J Biol Chem. 2021 Jan-Jun;296:100098.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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