Antitumor agent-107
Antitumor agent-107 (compound 5h) is an anticancer agent that shows excellent inhibitory activity against leukemia cell lines (GI50=0.32-1.34 μM) . Antitumor agent-107 also shows antitumor activity against various other human cancer cell lines (GI50 range 0.35-9.43 μM) [1].
Product Specifications
CAS Number
[3052360-22-9]
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-107.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=CC(C2=NC3=NC4=C(C=CC=C4)N3C(C5=CC=CC6=C5C=CC=C6)=C2)=C1)OC
Molecular Formula
C28H21N3O2
Molecular Weight
431.49
References & Citations
[1]Moataz A. Shaldam, et al. 2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profiling. Eur J Med Chem. 2023 Oct 5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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