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MGAT2-IN-4

MGAT2-IN-4 (compound 33) is an inhibitor of monoacylglycerol transferase 2 (MGAT2), with liver metabolic stability. MGAT2-IN-4 can be used for research on obesity, diabetes and non-alcoholic steatohepatitis (NASH) [1].

Product Specifications

CAS Number

1841424-92-7

UNSPSC

12352005

Target

Acyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/mgat2-in-4.html

Solubility

10 mM in DMSO

Smiles

O=C1NC(C2=CC=C(C3=CCC(C)(CC3)C)C=C2)=CC(C4=CC=C(C)C=C4)=C1C5=NN=NN5

Molecular Formula

C27H27N5O

Molecular Weight

437.54

References & Citations

[1]Moore F, et al. Discovery of novel pyridinones as MGAT2 inhibitors for the treatment of metabolic disorders. Bioorg Med Chem Lett. 2023 Jul 15;91:129362.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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