Npx-Au
Npx-Au is a NSAID–Au (I) complex with antitumor activity. Npx-Au can be used for the research of ovarian cancer[1]. Npx-Au is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
3036175-27-3
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/npx-au.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H](C1=CC2=C(C=C1)C=C(OC)C=C2)C)NCC#C[Au][P](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5
Molecular Formula
C35H31AuNO2P
Molecular Weight
725.57
References & Citations
[1]He Q, et al. Near-Infrared-Activatable PROTAC Nanocages for Controllable Target Protein Degradation and On-Demand Antitumor Therapy. J Med Chem. 2023 Jun 6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
